Risk of Contrast induced nephropathy in patients undergoing Primary coronary angioplasty
Background: Contrast induced nephropathy (CIN) is one of the common cause for hospital acquired renal failure in patients undergoing coronary angioplasty for acute myocardial infarction. The aim of this study was to assess the renal function in patients after primary coronary angioplasty by estimating the levels of serum creatinine (Sr. Cr)
Materials & Methods: Sample sizes of 51 subjects were included for the study. Serum creatinine levels were measured before and after the procedure. The difference in Serum creatinine levels was calculated.CIN was defined as increase in Sr Cr >0.5 or >25% compared to the baseline value.
Results: Out of the 51 cases, CIN occurred in 7.8% (4 cases). In addition,19.6 %( 10 cases) had pre-existing renal insufficiency out of which 3 subjects developed CIN.According to recently proposedÂ definition of contrast nephropathy 5.9 %(3 cases) and 7.8% (4 cases)Â were in grade 1and 2 respectively. Incidence of CIN in patients with diabetes mellitus was found to be statistically significant (p<0.05) as compared to patients without diabetes mellitus.
Conclusion: CIN is a common complication of primary coronary angioplasty. Its incidence is more in patients with pre existing renal insufficiency and diabetes mellitus compared to patients with normal renal function and without any underlying risk factors.
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